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337 results
arxiv.org πŸ“… 2004 πŸ“° arXiv πŸ“„ PDF
Geometric theory on the elasticity of bio-membranes
πŸ‘€ Z. C. Tu; Z. C. Ou-Yang

The purpose of this paper is to study the shapes and stabilities of bio-membranes within the framework of exterior differential forms. After a brief review of the current status in theoretical and experimental studies on the shapes of bio-membranes, a geometric scheme is proposed to discuss the shape equation of closed…

cond-mat.soft math-ph math.DG q-bio.QM
DOI: 10.1088/0305-4470/37/47/010
arxiv.org πŸ“… 2015 πŸ“° arXiv πŸ“„ PDF
A Mathematical Model for the Genetic Code(s) Based on Fibonacci Numbers and their q-Analogues
πŸ‘€ Tidjani Negadi

This work aims at showing the relevance and the applications possibilities of the Fibonacci sequence, and also its q-deformed or quantum extension, in the study of the genetic code(s). First, after the presentation of a new formula, an indexed double Fibonacci sequence, comprising the first six Fibonacci numbers, is sh…

q-bio.OT
arxiv.org πŸ“… 2023 πŸ“° arXiv πŸ“„ PDF
Drug Discovery under Covariate Shift with Domain-Informed Prior Distributions over Functions
πŸ‘€ Leo Klarner; Tim G. J. Rudner; Michael Reutlinger; Torsten Schindler; Garrett M. Morris; Charlotte Deane; Yee Whye Teh

Accelerating the discovery of novel and more effective therapeutics is an important pharmaceutical problem in which deep learning is playing an increasingly significant role. However, real-world drug discovery tasks are often characterized by a scarcity of labeled data and significant covariate shift$\unicode{x2013}\un…

q-bio.BM cs.LG stat.ML
arxiv.org πŸ“… 2008 πŸ“° arXiv πŸ“„ PDF
Efficiently Simulating Higher-Order Arithmetic by a First-Order Theory Modulo
πŸ‘€ Guillaume Burel

In deduction modulo, a theory is not represented by a set of axioms but by a congruence on propositions modulo which the inference rules of standard deductive systems---such as for instance natural deduction---are applied. Therefore, the reasoning that is intrinsic of the theory does not appear in the length of proofs.…

cs.LO cs.CC
DOI: 10.2168/LMCS-7(1:3)2011
arxiv.org πŸ“… 2006 πŸ“° arXiv πŸ“„ PDF
Similarity of Objects and the Meaning of Words
πŸ‘€ Rudi Cilibrasi; Paul Vitanyi

We survey the emerging area of compression-based, parameter-free, similarity distance measures useful in data-mining, pattern recognition, learning and automatic semantics extraction. Given a family of distances on a set of objects, a distance is universal up to a certain precision for that family if it minorizes every…

cs.CV cs.IR
arxiv.org πŸ“… 2025 πŸ“° arXiv πŸ“„ PDF
Learning Decomposed Contextual Token Representations from Pretrained and Collaborative Signals for Generative Recommendation
πŸ‘€ Yifan Liu; Yaokun Liu; Zelin Li; Zhenrui Yue; Gyuseok Lee; Ruichen Yao; Yang Zhang; Dong Wang

Recent advances in generative recommenders adopt a two-stage paradigm: items are first tokenized into semantic IDs using a pretrained tokenizer, and then large language models (LLMs) are trained to generate the next item via sequence-to-sequence modeling. However, these two stages are optimized for different objectives…

cs.IR cs.AI cs.CL
arxiv.org πŸ“… 2022 πŸ“° arXiv πŸ“„ PDF
Experimenting with Selected Automated Approaches for Bias Analysis
πŸ‘€ Gizem Gezici

This work first presents our attempts to establish an automated model using state-of-the-art approaches for analysing bias in search results of Bing and Google. Experimental results indicate that the current class-wise F1-scores of our best model are not sufficient to establish an automated model for bias analysis. Thu…

cs.IR
arxiv.org πŸ“… 2019 πŸ“° arXiv πŸ“„ PDF
Liquid phase separation controlled by pH
πŸ‘€ Omar Adame-Arana; Christoph A. Weber; Vasily Zaburdaev; Jacques Prost; Frank JΓΌlicher

We present a minimal model to study liquid phase separation in a fixed pH ensemble. The model describes a mixture composed of macromolecules that exist in three different charge states and have a tendency to phase separate. We introduce the pH dependence of phase separation by means of a set of reactions describing the…

physics.bio-ph cond-mat.soft
DOI: 10.1016/j.bpj.2020.07.044
arxiv.org πŸ“… 2011 πŸ“° arXiv πŸ“„ PDF
Subtle pH differences trigger single residue motions for moderating conformations of calmodulin
πŸ‘€ Ali Rana Atilgan; Ayse Ozlem Aykut; Canan Atilgan

This study reveals the essence of ligand recognition mechanisms by which calmodulin (CaM) controls a variety of Ca2+ signaling processes. We study eight forms of calcium-loaded CaM each with distinct conformational states. Reducing the structure to two degrees of freedom conveniently describes main features of conforma…

physics.bio-ph q-bio.BM
arxiv.org πŸ“… 2025 πŸ“° arXiv πŸ“„ PDF
Heaven & Hell: One-Step Hub Consensus
πŸ‘€ Nnamdi Daniel Aghanya

Many networked systems require a central authority to enforce a global configuration against local peer influence. We study influence dynamics on finite weighted directed graphs with a distinguished hub node and binary vertex states ('Glory' or 'Gnash'). We give a sharp, local, and efficiently checkable criterion that …

cs.SI
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